45 research outputs found

    Control Method for the Wind Turbine Driven by Doubly Fed Induction Generator Under the Unbalanced Operating Conditions

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    This thesis illustrates the principle and the behavior for doubly fed electric machines used in variable speed wind power systems under the balanced and unbalanced operating conditions. A generalized control method for complete stator pulsating power elimination and harmonic elimination in grid currents with adjustable power factor of a doubly fed induction generator under the unbalanced operating conditions is proposed. The theoretical analysis of this proposed control method is presented and then demonstrated by the simulation in Powersim®. The grid ride-through-fault ability by using the proposed method is also teste

    Research progress of neoantigen-based dendritic cell vaccines in pancreatic cancer

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    The mutation of the crucial genes such as tumor suppressors or oncogenes plays an important role in the initiation and development of tumors. The non-synonymous mutations in the tumor cell genome will produce non-autologous proteins (neoantigen) to activate the immune system by activating CD4+ and CD8+ T cells. Neoantigen-based peptide vaccines have exhibited exciting therapeutic effects in treating various cancers alone or in combination with other therapeutic strategies. Furthermore, antigen-loaded DC vaccines are more powerful in inducing stronger immune responses than vaccines generated by antigens and adjuvants. Therefore, neoantigen-based dendritic cell (DC) vaccines could achieve promising effects in combating some malignant tumors. In this review, we summarized and discussed the recent research progresses of the neoantigen, neoantigen-based vaccines, and DC-based vaccine in pancreatic cancers (PCs). The combination of the neoantigen and DC-based vaccine in PC was also highlighted. Therefore, our work will provide more detailed evidence and novel opinions to promote the development of a personalized neoantigen-based DC vaccine for PC

    CT-guided fine-needle localization of ground-glass nodules in re-aerated lung specimens: localization of solitary small nodules or multiple nodules within the same lobe

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    PURPOSEWe aimed to explore the value of localizing small ground-glass nodules (GGNs; <10 mm) or multiple GGNs within the same lobe in re-aerated lung specimens using CT-guided fine-needle localization.METHODSThirty-five lung specimens containing single small GGNs (<10 mm) and eight specimens containing two or more GGNs in the same lobe were re-aerated with an inflatable aerator. All lesions were localized via CT-guided fine-needle localization following re-aeration. The specimens were then sent for pathologic sampling and qualitative diagnosis.RESULTSAll 69 nodules from 43 cases were successfully localized using CT-guided fine-needle localization following re-aeration.CONCLUSIONSCT-guided fine-needle localization of lesions in surgical specimens under constant, moderate mechanical aeration allows for the rapid and accurate localization of lesions and helps avoid damage from preoperative localization

    Effect of steam reinjection mass flow rate on the SOFC–GT system with steam reinjection

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    A solid oxide fuel cell (SOFC) is regarded as the first choice of high-efficiency and clean power generation technology in the 21st century due to its characteristics of high power generation efficiency and low pollutant emission. In this paper, hydrogen is used as a fuel for SOFCs using the EBSILON platform. A sensitivity analysis of the solid oxide fuel cell–gas turbine (SOFC–GT) system with steam reinjection is carried out to investigate the effect of the steam reinjection mass flow rate on the improvement of the electrical efficiency of the system and on the values of the other parameters. The results show that the variation in the steam reinjection mass flow rate has an effect on other parameters. Changes in several parameters affect the electrical efficiency of the system, which reaches 74.11% at a pressure ratio of 10, SOFC inlet temperature of 783.15 K, turbine back pressure of 70 kPa, and steam reinjection mass flow rate of 6.16 kg/s. Future research can optimize the overall parameter selection of the system in terms of economy and other aspects

    Large expert-curated database for benchmarking document similarity detection in biomedical literature search

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    Document recommendation systems for locating relevant literature have mostly relied on methods developed a decade ago. This is largely due to the lack of a large offline gold-standard benchmark of relevant documents that cover a variety of research fields such that newly developed literature search techniques can be compared, improved and translated into practice. To overcome this bottleneck, we have established the RElevant LIterature SearcH consortium consisting of more than 1500 scientists from 84 countries, who have collectively annotated the relevance of over 180 000 PubMed-listed articles with regard to their respective seed (input) article/s. The majority of annotations were contributed by highly experienced, original authors of the seed articles. The collected data cover 76% of all unique PubMed Medical Subject Headings descriptors. No systematic biases were observed across different experience levels, research fields or time spent on annotations. More importantly, annotations of the same document pairs contributed by different scientists were highly concordant. We further show that the three representative baseline methods used to generate recommended articles for evaluation (Okapi Best Matching 25, Term Frequency-Inverse Document Frequency and PubMed Related Articles) had similar overall performances. Additionally, we found that these methods each tend to produce distinct collections of recommended articles, suggesting that a hybrid method may be required to completely capture all relevant articles. The established database server located at https://relishdb.ict.griffith.edu.au is freely available for the downloading of annotation data and the blind testing of new methods. We expect that this benchmark will be useful for stimulating the development of new powerful techniques for title and title/abstract-based search engines for relevant articles in biomedical research.Peer reviewe

    Imaging pulmonary infectious diseases in immunocompromised patients

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    Immunocompromised patients are subject to a variety of infectious pathogens involving lungs. Imaging examination of pulmonary conditions could provide valuable information for differentiation diagnosis, treatment assessment as well as prognostic prediction. Imaging manifestations of immunocompromise-related pulmonary diseases could be either pathogen-specific or -non-specific. It is particularly fundamental to recognize these imaging characteristics at suspicion of opportunistic infections in such patients. In this article, we attempt to present a review to refresh and update our knowledge of imaging features of pulmonary infectious diseases in immunocompromised patients

    Ride-Through Fault Generalized Control Method for a Wind Turbine Inverter

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    The growing share of installed wind capacity in transmission systems nowadays require wind turbines to remain connected to the grid during severe network disturbances as well as to provide efficient restoration to the pre-fault conditions. It is know that grid side inverters are sensitive to voltage disturbances which results in appearance of low order harmonics in line currents as well as a huge ripple on a DC link capacitor. This paper presents a generalized method for grid-fault ride-through control for a wind turbine inverter. An analytical approach for complete harmonic elimination in grid currents and DC link voltage with controllable power factor under extreme disturbances in the power system is proposed. To illustrate the proposed method, the simulation results of a variable speed wind turbine system with PM synchronous generator under severe faults are shown and compared to the results obtained by using a standard indirect current control method

    Ride-Through Fault Generalized Control Method for a Wind Turbine Inverter

    No full text
    The growing share of installed wind capacity in transmission systems nowadays require wind turbines to remain connected to the grid during severe network disturbances as well as to provide efficient restoration to the pre-fault conditions. It is know that grid side inverters are sensitive to voltage disturbances which results in appearance of low order harmonics in line currents as well as a huge ripple on a DC link capacitor. This paper presents a generalized method for grid-fault ride-through control for a wind turbine inverter. An analytical approach for complete harmonic elimination in grid currents and DC link voltage with controllable power factor under extreme disturbances in the power system is proposed. To illustrate the proposed method, the simulation results of a variable speed wind turbine system with PM synchronous generator under severe faults are shown and compared to the results obtained by using a standard indirect current control method
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